Researchers and scientists agree that aging is the natural result of overall cellular deterioration. One major way this occurs is through exposure to free radicals, other oxidants, and toxicological insults. It is impossible to avoid these exposures because the food you eat, the air you breathe, our modern lifestyles, stress, and even exercise, but we can do certain things to maintain our health as we age. The human body naturally fights these insults by producing its own antioxidant and detoxification enzymes through Nrf2-dependent mechanisms. However, as we grow older, Nrf2 works less efficiently. That’s where Protandim® Nrf2 Synergizer TM plays a critical role. It supports these Nrf2-dependent mechanisms to boost the body’s production of antioxidant and detoxification enzymes. Another natural phenomenon relating to the aging process is our mitochondria (the cell’s powerplant) begins working less efficiently. Less efficient mitochondria produce less energy and produce excess free radicals and other oxidants. Supporting overall mitochondrial function is important to promote overall health as we age. Protandim NRF1 was designed to both increase mitochondrial number and provide ingredients shown to support mitochondrial health. Lastly, another major significant effect of the aging process is a decline of cellular NAD levels and reduction of sirtuin activity. Sirtuin activity has been shown to play a major roll in supporting overall health. Protandim® NAD Synergizer TM was designed to support NAD levels and sirtuin activity. Thus, taking the entire Protandim family of products will help support all of these significant aspects of the aging process.*

Like flipping a light switch, Protandim NRF1 Synergizer instructs your cells to produce more mitochondria. And that gives your cells the energy you need to feel more active, alert, and younger. While free radicals continue to break down mitochondria with every breath, Protandim NRF1 helps support the cellular process of building those powerhouses back up, which promotes cellular health and supports healthy aging.*

• Acetyl L-Carnitine - An amino acid (a building block for proteins) that is naturally produced in the body. Acetyl L-Carnitine enhances either mitochondrial DNA (mtDNA) transcription, the stability of mitochondrial mRNA, or mitochondrial protein synthesis. Combined with Alpha Lipoic Acid, these two ingredients boost mitochondria production, support healthy cellular aging, and protect against normal oxidation of RNA and mitochondria.*
• Coenzyme Q10 — It is made in the body and resides primarily in mitochondria where it plays a key role in transporting electrons so ATP is made. Combined with Alpha Lipoic Acid, it supports cellular energy levels, stress response and antioxidant defense mechanisms.*
• Alpha-lipoic acid — Alpha lipoic acid, or ALA, is made in the body and helps to turn glucose into energy that the cell can use. ALA is able to neutralize free radicals because of its -thiol groups because it is both fat and water soluble, it can protect all parts of the cell (including the mitochondria) from these free radicals.*
• Grape Extract — This extract, made from the whole grape (seeds, pulp and skin), contains powerful natural polyphenols (flavanols) known to support healthy aging. The bioactives help activate the NRF1 protein and other biological pathways to maintain good health.*
• Quercetin — It is made in the body and resides primarily in mitochondria where it plays a key role in transporting electrons so ATP is made. Combined with Alpha Lipoic Acid, it supports cellular energy levels, stress response and antioxidant defense mechanisms.*

Protandim® Nrf2 & NRF1 Synergizers use ingredients to reduce oxidative stress and support mitochondria production to increase cellular health and in turn, helps support healthy aging.

Yes, we call this the Tri-Synergizer™!